UKUSETSHENZISWA OKUHLOSIWE
Isinyathelo Esiqinile^®I-HPV 16/18 Antigen Rapid Test Device iyi-assay ebonakalayo esheshayo yokutholwa kokuqagela kwekhwalithi ye-HPV 16/18 E6&E7 oncoprotein kuma-specimens we-swab yomlomo wesibeletho wesifazane.Le kit kuhloswe ngayo ukuthi isetshenziswe njengosizo ekuxilongweni komdlavuza weCervical Pre-Cancer kanye Nomdlavuza.

ISINGENISO
Emazweni asathuthuka, umdlavuza womlomo wesibeletho uyimbangela ehamba phambili yokufa kwabantu besifazane okuhlobene nomdlavuza, ngenxa yokuntuleka kokuqaliswa kokuhlolwa komdlavuza womlomo wesibeletho owandulela umdlavuza kanye nomdlavuza.Ukuhlolwa kokuhlolwa kwezilungiselelo zensiza ephansi kufanele kube lula, kusheshe, futhi kungabizi kakhulu.Ngokufanelekile, ukuhlolwa okunjalo kungaba ulwazi mayelana nomsebenzi we-HPV oncogenic.Ukuvezwa kwakho kokubili i-HPV E6 ne-E7 oncoprotein kubalulekile ukuze uguquko lwamangqamuzana omlomo wesibeletho lwenzeke.Eminye imiphumela yocwaningo ibonise ukuhlobana kwe-E6 & E7 oncoprotein positivity nabo bobabili ubukhali be-histopathology yomlomo wesibeletho kanye nengozi yokuqhubeka.Ngakho-ke, i-E6&E7 i-oncoprotein ithembisa ukuba i-biomarker efanele yomsebenzi we-oncogenic we-HPV.

ISIMISO
Isinyathelo Esiqinile^®I-HPV 16/18 Antigen Rapid Test Device yakhelwe ukuthola i-HPV 16/18 E6&E7 Oncoprotein ngokutolikwa okubonakalayo kokuthuthukiswa kombala emgqeni wangaphakathi.I-membrane yayinganyakazi ngamasosha omzimba e-monoclonal anti-HPV 16/18 E6&E7 endaweni yokuhlola.Ngesikhathi sokuhlolwa, isifanekiso sivunyelwe ukuthi sisabele ngama-anti-HPV 16/18 E6&E7 amasosha omzimba anemibala ehlanganisiwe yama-partticals conjugates, ayefakwe ngaphambili kusampula yesampula yokuhlolwa.Ingxube ibe isihamba kulwelwesi ngesenzo se-capillary, bese ixhumana nama-reagents kulwelwesi.Uma bekunama-oncoprotein e-HPV 16/18 E6&E7 eyanele kumasampula, ibhande elinemibala lizokwakheka endaweni yokuhlola yolwelwesi.Ukuba khona kwaleli bhande elinemibala kubonisa umphumela omuhle, kuyilapho ukungabikho kwawo kubonisa umphumela omubi.Ukubukeka kwebhande elinemibala endaweni yokulawula kusebenza njengokulawula kwenqubo.Lokhu kubonisa ukuthi umthamo ofanele we-specimen wengeziwe futhi i-membrane wicking yenzekile.

UKUQOQWA KANYE NESIGCINISO
■ Izinga lesampula elitholiwe libaluleke kakhulu.Kangango baI-epithelial cell yomlomo wesibeletho kufanele iqoqwe nge-swab.Ngezibonelo zomlomo wesibeletho:
■ Sebenzisa kuphela i-Dacron noma i-Rayon enezici eziyinyumba ezinezinsimbi zepulasitiki.Ikonabatusa ukusebenzisa i-swab ehlinzekwa ngumkhiqizi wakhithi (I-swab areokungaqukethwe kule kit, ukuze uthole imininingwane yoku-oda, sicela uthinteumkhiqizi noma umsabalalisi wendawo, inombolo yekhathalogi ithi 207000).Ama-swabskusuka kwabanye abahlinzeki akuqinisekisiwe.Ama-swabs anezeluleko zikakotini nomaama-shafts okhuni awanconywa.
■ Ngaphambi kokuqoqwa kwesampula, susa amafinyila amaningi endaweni yomlomo wesibelethonge-swab ehlukile noma ibhola likakotini bese ulahla.Faka i-swab ku-umlomo wesibeletho kuze kube yilapho imicu engezansi kuphela isobala.Zungezisa ngokuqinile i-swabimizuzwana engu-15-20 ohlangothini olulodwa.Khipha i-swab ngokucophelela!
■ Ungabeki i-swab kunoma iyiphi into yokuthutha equkethe okuphakathi kusukela ngaleso sikhathiezokuthutha ziphazamisa ukuhlolwa nokusebenza kwezinto eziphilayoayidingeki ekuhlolweni.Beka i-swab ku-tube yokukhipha, uma ukuhlolwaingase igijime ngokushesha.Uma ukuhlolwa okusheshayo kungenakwenzeka, isiguliamasampula kufanele afakwe kushubhu ezomile ezokuthutha ukuze zigcinwe noma zithuthwe.Iama-swabs angase agcinwe amahora angu-24 ekamelweni lokushisa (15-30°C) noma isonto elilodwaku-4°C noma kungabi ngaphezu kwezinyanga eziyisi-6 ku -20°C.Zonke izifanekiso kufanele zivunyelweukufinyelela izinga lokushisa ekamelweni lika-15-30 ° C ngaphambi kokuhlolwa.