Umhlaba owodwa munye ukulwa
Ukubambisana kwe-Insinceternational ukwakha umphakathi womhlaba wonke wesikhathi esijwayelekile esiphendula kwi-Covid-19 Phristic Hink
I-novel coronavirus eshanela kulo lonke izwe iholele enkingeni yenhlekelele eqhubekayo ye-covil-19. I-novel coronavirus ayinamingcele, alikho izwe elizosinda kule mpi ngokumelene ne-Covion-19. Ukuphendula lo bhubhane lomhlaba wonke lwe-Covid-19 Ubhubhane, imikhiqizo ye-Liming Bio-Corp yenza iminikelo ukusekela inhlala-kahle yemiphakathi yethu yomhlaba wonke.
Umhlaba wethu njengamanje ubhekene nomthelela ongakaze ubonwe yisifo soveli coronavirus isifo sika-2019 (Covid-19) ubhubhane. Kuze kube manje, asikho isidakamizwa esisebenza kahle sokwelashwa kwalesi sifo. Kodwa-ke, izivivinyo eziningi zokuxilonga zenzelwe ukutholwa kwe-Covid-19. Lezi zivivinyo zisuselwa ezindleleni ze-molecular noma ze-terological ukuthola i-novel coronavirus ethize noma i-antibody biomarkers. Njengoba i-Covid-19 isifinyelele esimweni sezinhlamvu, ukutholakala kwesifo sokuqala sonoveli kubalulekile ekuhloleni ukusakazeka kwegciwane futhi kuqukethe, kepha isivivinyo esifanelekile sokusetshenziswa kwendawo yonke asikho. Kufanele sazi ukuthi yiziphi izivivinyo ezingasetshenziselwa ukuhlolwa, ukuxilongwa kanye nokubheka ukutheleleka kwe-covid-19, futhi kuyini ukulinganiselwa kwabo. Kubaluleke kakhulu ukuthi ungawasebenzisa kangcono la mathuluzi esayensi futhi usize ukukhomba nokulawula ukuvela kwalokhu kusakazeka okusheshayo nokugula okungathi sína.
Inhloso yokutholwa kwe-coronavirus yenoveli ukuthola ukuthi umuntu othelelekile - okuthelelekile okungu-19 noma umthwali we-asymptotic ongakwazi ukusabalalisa buthule buthule, ukuhlinzeka ngemininingwane ebalulekile ukuqondisa izinqumo zokwelashwa kwemitholampilo. Izifundo ezedlule zikhombisile ukuthi ama-70% ezinqumo zemitholampilo ancike emiphumeleni yokuhlola. Lapho kusetshenziswa izindlela ezihlukile zokutholwa, izidingo zamakhithi we-realegent yokutholwa nawo ahlukile.
Umdwebo 1
Umdwebo1:Umdwebo okhombisa izigaba ezibalulekile zamazinga ajwayelekile we-biomarker ngesikhathi esijwayelekile sezinto zokutheleleka nge-17. I-X-axis ikhombisa inani lezinsuku zokutheleleka, futhi i-y-axis ikhombisa umthwalo wegciwane, ukugxila kwama-antigen, kanye nokuhlushwa kwamasosha omzimba ezikhathini ezahlukene. I-Antibody isho ama-antibodies we-IGM ne-IGG. Womabili ama-RT-PCR nokutholwa kwe-Antigen asetshenziselwa ukuthola ubukhona noma ukungabikho kwe-coronavirus yenoveli, okuwubufakazi obuqondile bokutholwa kwesiguli kusenesikhathi. Kungakapheli isonto lokutheleleka ngegciwane, ukutholwa kwe-PCR, noma ukutholwa kwe-Antigen. Ngemuva kokutheleleka kwenoveli ye-coronavirus cishe izinsuku eziyi-7, i-antibody ye-IGM ngokumelene kancane kancane iColonavirus inyuke kancane kancane egazini lesiguli, kepha isikhathi sokuba khona sifushane, futhi ukuhlushwa kwaso kuncipha ngokushesha. Ngokuphambene nalokho, i-IGG antibody ngegciwane livela kamuva, imvamisa cishe ezinsukwini eziyi-14 ngemuva kokutheleleka ngegciwane. Ukuhlushwa kwe-IGG kancane kuyanda, futhi kuyaqhubeka isikhathi eside egazini. Ngakho-ke, uma i-igm itholakala egazini lesiguli, kusho ukuthi leli gciwane lisanda kutheleleka, okuwukumaka ukutheleleka kusenesikhathi. Lapho i-IGG antibody itholakala egazini lesiguli, kusho ukuthi ukutheleleka ngegciwane bekukhona isikhashana. Kubizwa nangokuthi ukutheleleka sekwedlule isikhathi noma ukutheleleka kwangaphambilini. Kuvame ukubonwa ezigulini ezisesigabeni Sokubuyisa.
Ama-biomarker of novel coronavirus
Inoveli coronavirus yigciwane le-rna, elihlanganiswa amaprotheni nama-nucleic acid. Leli gciwane lihlasela umzimba womsingathi (lomuntu), lingena kumaseli ngesayithi elibophayo elihambisanayo i-receptor ace2, futhi liphindaphinda kumaseli wokusingathwa, okwenza amasosha omzimba womuntu aphendule kwabahlaseli bakwamanye amazwe futhi akhiqize amasosha omzimba athile. Ngakho-ke, ama-vial nucleic acid kanye nama-antigen, nama-antibodies athile amelene nenoveli coronavirus angasetshenziswa ngokweqiniso njenge-biomarkers ekhethekile yokutholwa kwe-coronavirus yenoveli. Ngokutholwa kwe-nucleic acid, ubuchwepheshe be-RT-PCR buvame ukusetshenziswa kakhulu, kanti izindlela ze-terological zivame ukusetshenziselwa ukutholwa kwama-antibodies ancanyana amanoveli. Njengamanje, kunezinhlobonhlobo zezindlela zokuhlola ezitholakalayo esingazikhethela ekuhlolweni kwezifo ze-Covid-19 [1].
Izimiso eziyisisekelo zezindlela eziphambili zokuhlola zenoveli coronavirus
Ukuhlolwa okuningi kokuxilonga kwe-Covid_19 kuyatholakala kuze kube manje, ngamakhithi amaningi wokuhlola athola imvume ngaphansi kokugunyazwa kokusetshenziswa kwezimo eziphuthumayo nsuku zonke. Yize intuthuko entsha yokuhlola iphuma namagama namafomethi amaningi ahlukahlukene, zonke izivivinyo zamanje ze-covion_19 zincike ebuchwepheshe obukhulu obukhulu: Ukutholwa kwe-nucleic acid nge-antibodies athile athile (Igm ne-IGG).
01. Ukutholwa kwe-nucleic acid
Ukubuyisela emuva ukubhala - ukusabela kwe-polymerase chain (RT-PCR), i-loop-mediated asthermal Amplification Amplification (isibani), nokulandelana kwesizukulwane esilandelayo (ama-NGS) yizindlela ezijwayelekile ze-nucleic acid zokutholwa kwenoveli coronavirus rna ukutholwa kwe-coronavirus rna. I-RT-PCR uhlobo lokuqala lokuhlolwa kwe-Covid-19, enconywe yi-World Health Organisation (WHO) kanye ne-US Center for Izifo kanye nokuvimbela (CDC).
02.serological antilody detection
I-Antibody iyiprotheni evikelayo ekhiqizwa emzimbeni womuntu ukuphendula ukutheleleka ngegciwane. I-IGM uhlobo lwakudala lwe-antibody kanti i-iGG luhlobo lwangempela lwe-antibody. Isampula ye-serum noma ye-plasma ivame ukuhlolwa ngokuba khona kwezinhlobo ezithile ze-IGM ne-IGG ye-antibody yokuhlola izigaba ezivuselelayo nezivuthayo ze-19. Lezi zindlela zokutholwa okususelwa ku-antibody zifaka i-colloidal igolide immunochromatography Assay, i-latex noma i-fluorescent microsphere imunochrofography, i-enzyme-lixhumanisa i-immunosorbent assay (elisa), kanye ne-chemiluminencences assay.
03.viral antigen ukutholwa
I-Antigen yisakhiwo esikuleli gciwane esamukelwa ngumzimba womuntu okubangela uhlelo lokuvikela ukuzivikela ekukhiqizeni amasosha omzimba ukusula leli gciwane egazini nasezicubu. I-antigen enegciwane ekhona kuleli gciwane ingabhekiswa futhi itholakale ngokusebenzisa iMmunoassay. Njengo-RNA we-viral, ama-antigen amagciwane nawo akhona kwipheshana lokuphefumula labantu abanegciwane futhi angasetshenziselwa ukuthola isigaba esibuhlungu sokutheleleka nge-covid-19. Ngakho-ke, kuvame ukunconyelwa ukuqoqa ama-apper repiratory aspecimen afana namathe, ama-nasopharyngeal kanye nama-sputum, i-sputum ejulile, i-bronchoalveolar lavage fluid (balf) yokuhlolwa kokuqala kwe-antigen.
Ukukhetha izindlela zokuhlola zenoveli coronavirus
Ukukhetha indlela yokuhlola kubandakanya izici eziningi, kufaka phakathi ukulungiselelwa kwekhwalithi, ukuhlolwa kwekhwalithi yekhwalithi, isikhathi sokuguqula, izindleko zokuhlola, izindlela zokuqoqa amasampula, izidingo zezobuchwepheshe zelebhu, indawo nezidingo zemishini. Ukutholwa kwama-nucleic acid noma ama-antigen amagciwane ukuhlinzeka ubufakazi obuqondile bokuba khona kwamagciwane futhi uqinisekise ukuxilongwa kokutheleleka kwe-coronavirus anoveli. Yize kunezindlela eziningi zokutholwa kwe-antigen, ukuzwela kwazo kwe-coronavirus yenoveli kuphansi kakhulu kunalokho kwe-RT-PCR Amplification. Ukuhlolwa kwe-Antibody kungukutholwa kwama-antibodies alwa namagciwane akhiqizwa emzimbeni womuntu, okuhlala isikhathi eside ngesikhathi futhi akunakusetshenziselwa ukutholwa kusenesikhathi ngesikhathi sokutheleleka ngegciwane. Ukuhlelwa komtholampilo kwezicelo zokutholwa kungahluka, futhi amasayithi aqoqa amasampula nawo angahluka. Ukutholwa kwamagciwane acid ama-acidi amagciwane kanye nama-antigen, isibonakaliso sidinga ukuqoqwa epheshana lokuphefumula lapho i-virus ikhona khona, njenge-nasopharyngeal swabs, i-sputum, noma i-bronchoallolar lavage fluid (balf). Ukutholwa okususelwa ku-antibody, isibonakaliso segazi kudingeka siqoqwe futhi sihlolwe ngokuba khona kwe-anti-virus antibody (IGM / IGG). Kodwa-ke, i-antibody kanye nemiphumela yokuhlolwa kwe-nucleic acid ingahlehlulelana. Isibonelo, lapho umphumela wokuhlola ungeyena ne-acid-acid-negative kodwa e-IGG-positive, le miphumela ikhombisa ukuthi isiguli okwamanje asiphathi naleli gciwane, kodwa selitholile kusukela ekuthelelekeni kwe-coronavirus. [2]
Izinzuzo nobubi bokuhlolwa kwenoveli coronavirus
Esihlokweni esinqunyelwe kanye nokwelashwa kwe-Novel CORONAVIRUS PNOUMONIA (Uhlobo lweSivivinyo7) (ekhishwe yi-National Health Commission kanye nokuphathwa kombuso komuthi wendabuko waseChina ngoMashi 3, 2020), Ukuhlolwa kwe-nucleic acid kusetshenziswa njengendlela ejwayelekile yegolide yokuthola inoveli Ukutheleleka kweCoronavirus, ngenkathi ukuhlolwa kwe-antibody nakho kubhekwa njengenye yezindlela zokuqinisekisa zokuxilongwa.
Ukutholwa kwe-pathogenic ne-serological
. Kunembe kakhudlwana uma ama-specimens atholakala epheshana lokuphefumula eliphansi (i-sputum noma i-air tract extraction). Ama-specimens kufanele athunyelwe ukuze ahlolwe ngokushesha okukhulu ngemuva kokuqoqwa.
. I-IGG ifinyelela ekuphakanyisweni kokuncishiswa okungenani okungu-4 ngesikhathi sokuhlanganisa ngokuqhathaniswa nesigaba esibuhlungu.
Kodwa-ke, ukukhethwa kwezindlela zokuhlola kuya ngezindawo zendawo, imithetho yezokwelapha, nezilungiselelo zomtholampilo. E-USA, i-NIH ikhiphe izifo zokwelashwa zikaCoronavirus 2019 (I-Covid-19) (Isayithi Kuvuselelwe: Ephreli 21,2020) kanye ne-FDA 2020) Ukuhlolwa kwezivivinyo ze-coronavirus-2019 ngesikhathi esiphuthumayo sempilo yomphakathi (kukhishwe ngoMashi 16,2020 ), lapho kuhlolwa ama-antibogies we-IGM / IGG akhethwe kuphela njengovivinyo lokuhlola.
Indlela yokutholwa kwe-nucleic acid
I-RT_PCR iyi-nucleic acid ebucayi kakhulu eyenzelwe ukuthola ukuthi ngabe inoveli coronavirus rna iyikhona yini noma cha endaweni yokuphefumula noma kolunye uhlobo. Umphumela wokuhlolwa kwe-PCR omuhle kusho ukuba khona kwenoveli coronavirus rna kwisampula ukuqinisekisa ukutheleleka kwe-covid-19. Umphumela wokuhlolwa kwe-PCR engemihle awusho ukuthi ukungabikho kwegciwane ngoba kungathinteka ngekhwalithi yesampula empofu noma indawo yesikhathi sezifo esigabeni esatholakele, njll. Yize i-RT-PCR iyivivinyo elibucayi kakhulu, inezinkinga eziningana. Ukuhlolwa kwe-RT-PRC kungaba yimisebenzi-ebanzi futhi kudle isikhathi, kuncike emfuhlakeni esezingeni eliphakeme lesampula. Lokhu kungaba yinselelo ngoba inani le-RNA elibangelwa yi-RNA alifani kakhulu phakathi kweziguli ezahlukene kepha futhi lingahluka ngaphakathi kwesiguli esifanayo ngokuya ngamaphoyinti wesikhathi lapho izigaba zokutheleleka. Ukuthola i-coronavirus yenoveli kudinga ama-specidimen asezingeni eliphakeme aqukethe inani elanele le-rna i-rna.
Ukuhlolwa kwe-RT-PCR kungenza umphumela ongemuhle ongalungile (amanga amanga) kwezinye iziguli ezine-covion-19 ukutheleleka. Njengoba sazi, izingosi eziphambili zokutheleleka ze-coronavirus yenoveli zitholakala emaphashini naseqeshweni eliphansi lokuphefumula, njenge-alveoli ne-bronchi. Ngakho-ke, i-sputum specimen kusuka ekukhwehleni okujulile noma i-bronchoalleolar lavage fluid (balf) icatshangelwe ukuthi inokuzwela okuphezulu kakhulu kokutholwa kwegciwane. Kodwa-ke, ekusebenzeni kwemitholampilo, amasampula avame ukuqoqwa kusuka epheshana lokuphefumula elingaphezulu ngokusebenzisa ama-nasopharyngeal noma ama-aropharyngeal swabs. Ukuqoqa lezi zinhlobo ze-specimens akukukhululeki kuphela ezigulini kodwa futhi kudinga abasebenzi abaqeqeshiwe ngokukhethekile. Ukwenza isampula ngaphansi kokuhlaselwa noma kube lula, kwezinye izikhathi iziguli zinikezwe i-swab yomlomo futhi zivume ukuthi zithathe isampula mucosa noma ngolimi olukuchitha. Ngaphandle kwe-RNA eyanele ye-RNA, i-RT-QPCR ingabuyisa umphumela wokuvinjwa okungalungile. Esifundazweni saseHubei, iChina, ukuzwela kwe-RT-PCR ekutholweni kokuqala kwabikwa ngo-30% -50%, ngesilinganiso samaphesenti angama-40. Izinga eliphakeme le-fral-negative kungenzeka ukuthi libangelwa isampula enganele.
Ngaphezu kwalokho, ukuhlolwa kwe-RT-PCR kudinga abasebenzi abaqeqeshiwe kakhulu ukwenza izinyathelo zokukhishwa kwe-RNA eziyinkimbinkimbi nenqubo ye-PCR Amplification. Kubuye kudinga izinga eliphakeme lokuvikelwa kwe-biosafety, indawo ekhethekile yelebhu, kanye nensimbi yesikhathi sangempela se-PCR. E-China, ukuhlolwa kwe-RT-PCR ye-Covid-19 Ukutholwa kudinga ukwenziwa ema-laboosafety level level 2 (BSL-2), ngokuvikelwa kwabasebenzi kusetshenziswa umkhuba we-biosafety level 3 (BSL-3). Ngaphansi kwalezi zidingo, kusukela ekuqaleni kukaJanuwari kuya ekuqaleni kukaJanuwari 2020, umthamo we-CICH Wuhan Laboratory wakwazi ukuthola amacala angamakhulu ambalwa ngosuku. Imvamisa, lokhu bekungeke kube yinkinga lapho kuhlolelwa ezinye izifo ezithathelwanayo. Kodwa-ke, lapho ubhekene nobhubhane lomhlaba wonke njenge-covion-19 ngezigidi zabantu ukuthi zihlolwe, i-RT-PCR iba yinkinga ebucayi ngenxa yezidingo zayo zelebhu noma imishini yezobuchwepheshe. Lokhu kububi kungakhawulela i-RT-PCR ukuthi isetshenziswe njengethuluzi elisebenzayo lokuhlola, futhi futhi lingahle liholele ekubambezelweni emibikweni yemiphumela yokuhlola.
Indlela Ye-Serological Antilody Ukutholwa
Ngenqubekela phambili yesifundo sezifo, ikakhulukazi ezigabeni eziphakathi nendawo futhi sekwephuzile, izinga lokutholwa kwe-antibody liphezulu kakhulu. Isifundo esibhedlela saseWuhan Central South sikhombise ukuthi izinga lokutholwa kwe-antibomvud lingafinyelela ngaphezu kwama-90% evikini lesithathu lokutheleleka nge-19. Futhi, i-antibody ingumkhiqizo wokuphendula umzimba womuntu ngokumelene nenoveli coronavirus. Ukuhlolwa kwe-antibody kunikeza izinzuzo eziningana ngaphezulu kwe-RT-PCR. Okokuqala, izivivinyo ze-serological antibody zilula futhi zishesha. Ukuhlolwa kwe-antibody Latelal Flow Test kungasetshenziselwa ukunakekelwa kokuletha umphumela ngemizuzu engu-15. Okwesibili, ilitshe elitholwe isivivinyo se-serological yi-antibody, eyaziwa ngokuthi iqinile kune-RNA ye-Viral. Ngesikhathi sokuqoqwa, ezokuthutha, ukugcinwa nokuhlola, ama-specimens okuhlolwa kwe-antibody ngokuvamile azinze ngokwedlula ama-specimens we-RT-PCR. Okwesithathu, ngoba i-antimwoyy isatshalaliswa ngokulinganayo ekujikelezweni kwegazi, kunokuhlukahluka okulula kwesampula kuqhathaniswa nokuhlolwa kwe-nucleic acid. Ivolumu yesampula edingekayo ekuhlolweni kwe-antibody incane. Isibonelo, i-microliter eyi-10 yeGazi eliPrick-Prick yanele ukusetshenziswa ku-Antibody Lateral Flow Test.
Ngokuvamile, ukuhlolwa kwe-antibody kukhethwa njengethuluzi lesengezo lokutholwa kwe-nucleic acid ukuthuthukisa izinga lokutholwa kwe-coronavirus yenoveli ngesikhathi sezifundo zezifo. Lapho ukuhlolwa kwe-antibody kusetshenziswa kanye nokuhlolwa kwe-nucleic acid, kungakhuphula ukunemba okubonakalayo kokuxilongwa kwe-covion19 ngokunciphisa imiphumela engemihle nemiphumela engamanga. Umhlahlandlela Wokusebenza Kwamanje awuncomi ukusebenzisa izinhlobo ezimbili zokuhlola ngokwehlukile njengefomethi yokuthola okuzimele kepha kufanele isetshenziswe njengefomethi ehlangene. [2]
Umdwebo2:Ukuhunyushwa okulungile kwe-nucleic acid kanye ne-antibody test imiphumela yokuthola ukutheleleka kwe-novel coronavirus
Umdwebo 3:I-Liming Bio-Products Co, Ltd. - Inoveli coronavirus IGM / Igg antibody Dual Rapid Test Kit (Grontstep®I-SARS-Cov-2 i-IGM / IGG Antibody Rapid Test, I-Latex Immunochrotography)
Umdwebo 4:Imikhawulo ye-Bio-Products Co, Ltd. - I-Strongstep®Inoveli coronavirus (SARS-Cov-2) I-Multiplex real-time PCR KIT (ukutholwa kofuzo ezintathu, indlela ye-Fluorescent Probe).
Qaphela:Le kit ebucayi kakhulu, elungele ukusetshenziswa kwe-PCR KIT iyatholakala ngefomethi ye-Lyophilesed (i-Freeze-yomiswa inqubo) ukuze isitoreji isikhathi eside. Ikhithi ingathuthwa futhi igcinwe emazingeni okushisa asekamelweni futhi iqinile unyaka owodwa. I-tube ngayinye ye-Premix iqukethe yonke i-reagents edingekayo ye-PCR Amplification, kufaka phakathi i-Reverse-Transcrate, ama-POPPS, ama-substrate, ama-dntps, ama-substrates.users angakwazi ukumane abuyiselwe ukuxubana nge-PRCR-grade kanye nethempulethi bese ulayisha kudivayisi ye-PCR ukuqhuba ukukhuliswa.
Ephendula ukuqubuka kwenoveli ye-coronavirus, imikhiqizo ye-ling bio-imikhiqizo Co, Ltd isebenze ngokushesha ukuthuthukisa amakhithi amabili wokuxilonga ukunika amandla ama-latoratories ezempilo emtholampilo ukuze athole ukuxilonga ukutheleleka kwezempilo oku-19. Lawa ma-kits alungele ukusetshenziswa ekuhlolweni okukhulu kwamazwe amaningi nasezifundeni lapho ukuqubuka kwenoveli coronavirus kusakazeka ngokushesha, futhi ukuhlinzeka ngokuxilonga nokuqinisekiswa kokutheleleka kwe-COVID-19. Lawa ma-kits asetshenziswa kuphela ngaphansi kokugunyazwa kokusetshenziswa kwezimo eziphuthumayo kwangaphambili (Peua). Ukuhlolwa kukhawulelwe ezindaweni zokusebenzela eziqinisekiswe ngaphansi kwemithethonqubo yeziphathimandla zikazwelonke noma zendawo.
Indlela Yokutholwa Kwe-Antigen
1. Ukutholwa kwegciwane le-antigen kuhlukaniswa esigabeni esifanayo sokutholwa okuqondile njengokutholwa kwe-nucleic acid. Lezi zindlela zokutholwa eziqondile zibheka ubufakazi bamagciwane amagciwane ku-specimen futhi ungasetshenziselwa ukuxilongwa kwesiqinisekiso. Kodwa-ke, ukuthuthukiswa kwamakhithi okutholwa kwe-Antigen kudinga izinga eliphakeme lamasoshabodies e-monoclonal anobudlelwano obuqinile nozwela oluphezulu olukwazi ukubona nokuthwebula amagciwane e-pathogenic. Imvamisa kuthatha izinyanga ezingaphezu kweziyisithupha ukukhetha nokwandisa i-monoclonal antibody efanele ukusetshenziswa kwikhithi yokutholwa kwe-antigen.
2. Njengamanje, ama-reagents wokutholwa okuqondile kwe-coronavirus yenoveli asaphansi kokucwaninga kanye nesigaba sokuthuthuka. Ngakho-ke, akukho kit yokutholwa kwe-antigen eqinisekiswe ngokomtholampilo futhi kutholakala kwezentengiso. Yize ngaphambili kubikwa ukuthi ifemu lokuxilonga eShenzhen lisungule ikhithi lokutholwa kwe-Antigen futhi lihlolwe emtholampilo eSpain, ukuthembeka kwe-Assay ngokunemba kwalo akunakuqinisekiswa ngenxa yokuba khona kwezinkinga zekhwalithi ye-reagent. Kuze kube manje, i-NMPPA (eyayiyi-China FDA) ayivumanga noma iyiphi ikhithi yokutholwa kwe-Antigen ngokusetshenziswa kwemitholampilo okwamanje. Sekuphetha, kwakhiwa izindlela ezahlukahlukene zokutholwa. Indlela ngayinye inezinzuzo nokulinganiselwa kwayo. Imiphumela evela ezindleleni ezahlukahlukene ingasetshenziselwa ukuqinisekiswa kanye nokuhleleka.
3. Ukukhiqiza ikhithi yekhwalithi ye-Covid-19 Test Kit kuncike kakhulu ekusebenzeni ngesikhathi sokucwaninga nentuthuko. I-Liming Bio-Product Co, Ltd. Ama-kits wokuhlola ayadingeka ukuze ahlangabezane namazinga okulawula asemqoka nasekuqinisekiseni ukuthi anikeza amazinga aphezulu okusebenza nokuvumelana. Ososayensi e-Liming Bio-Product Co, Ltd banazo izipiliyoni zeminyaka engamashumi amabili ekwakheni, ekuhlolweni nasekuboneni ku-Vitro Divicostic Kits ukuqinisekisa ukusebenza okuphezulu kakhulu ekuhlazisweni kokuhlaziya.
Ngesikhathi sobhubhane lwe-Covil-19, uhulumeni waseChina wabhekana nokuhlinzwa okukhulu kwezidingo zokuvimbela ubhubhane ezitolo zamazwe aphesheya. Ngo-Ephreli 5, engqungqutheleni yabezindaba yoMkhandlu WoMkhandlu WoMkhandlu Wokuvimbela Nokulawula "ukuqinisa ukuphathwa kwekhwalithi yezinto zokwelashwa kanye nokulawula ukuhlelwa kwemakethe", iJiang Fan, umhloli wezinga lokuqala uMnyango Wezemisebenzi Yamanye Amazwe Kwezentengiselwano, kusho, "Ngokulandelayo, sizogxila emizamweni yethu ngezinto ezimbili, okokuqala, ukusheshisa ukusekelwa kwezinto ezengeziwe zokwelashwa ezidingekayo ngumphakathi wamazwe omhlaba, futhi, ukuthuthukisa ukulawulwa kwekhwalithi, umthetho, kanye nokuphathwa kwemikhiqizo. Sizokwenza umnikelo weChina waphendukela ngokuhlanganyela kulo bhubhane lomhlaba wonke futhi wakhe umphakathi ngekusasa elalihlanganyela esintwini.
Umdwebo 5:I-Liming Bio-Products Co, i-Novel. Inoveli ye-coronavirus realegent ithole isitifiketi sokubhaliswa kwe-EU CE
Isitifiketi sokuhlonishwa
Housenhan
Umdwebo 6 I-Wuhan Vulcan Vulcan Mountain Hospital iyisibhedlela esaziwa kakhulu eChina esikhethekile ekwelapheni i-Covil Covid - iziguli eziyi-19.
Njengoba ukuqubuka kwenoveli coronavirus kuyaqhubeka ukusakazeka emhlabeni wonke, ama-nanjing liming bio-prots Co, Ltd. Uyakhuphuka ukusekela nokusiza imiphakathi emhlabeni wonke ngobuchwepheshe bethu bokuqala ukulwa nalesi sisongo somhlaba wonke sokulwa nomhlaba wonke ukulwa nalolu songo emhlabeni. Ukuhlolwa okusheshayo kokutheleleka kwe-Covid-19 kuyingxenye ebucayi yokubhekana nalokhu kusongela. Siyaqhubeka nokufaka isandla ngendlela ebalulekile ngokunikeza amapulatifomu aphezulu aphezulu ezandleni zabasebenzi bezempilo bangaphambili ukuze abantu bathole imiphumela yokuhlola ebucayi abayidingayo. I-Limpleng Bio-Products Co, Ltd. Imizamo yempi yokulwa nobhubhane lweCovid-19 ukunikela ubuchwepheshe bethu, okuhlangenwe nakho, kanye nobungcweti emiphakathini yamazwe omhlaba ekwakhiweni komphakathi womhlaba wonke.
Cindezela isikhathi eside ~ scan bese usilandela
I-imeyili: sales@limingbio.com
Iwebhusayithi: https://limingbio.com
Isikhathi sePosi: Meyi-01-2020
